Reproductive Disorders

Women’s reproductive health is impacted by a range of disorders, including hormonal conditions like polycystic ovary syndrome (PCOS), endometriosis, and primary ovarian insufficiency, which affect fertility and menstrual cycles. Structural issues such as uterine fibroids, Müllerian anomalies, and pelvic organ prolapse can lead to pain, pregnancy complications, or infertility. Menstrual disorders like dysmenorrhea, menorrhagia, and amenorrhea disrupt normal cycles, while infectious diseases such as pelvic inflammatory disease (PID) and sexually transmitted infections (STIs) can cause long-term reproductive damage. Autoimmune and genetic disorders, including Turner syndrome, congenital adrenal hyperplasia, and lupus, may affect puberty, ovarian function, or pregnancy outcomes. Pregnancy-related conditions like preeclampsia, gestational diabetes, and recurrent pregnancy loss pose risks for both mother and baby. Cancers of the reproductive system (cervical, ovarian, and endometrial) and sexual dysfunction disorders (vaginismus, dyspareunia) further impact reproductive well-being. Additionally, pubertal defects like delayed puberty or precocious puberty result from hormonal imbalances or genetic conditions, affecting development and future fertility.
Faculty:
Jonathan Butcher: medical device technology design, soft tissue biomechanics, cardiovascular disease
Barbara Chubak, MD: sexual dysfunction, regenerative medicine, cosmetic genital surgery, bioethics
Ben Cosgrove: female reproductive lifespan, ovarian and endometrial cancers, musculoskeletal dysfunction
Arunika Das: reproductive aging, early pregnancy loss, embryo development
Callum Donnelly: metabolic syndrome effect on fertility and pregnancy
Tamatha Fenster, MD: pelvic surgery, women’s health technology innovation
Melissa Frey: genetic predisposition to gynecologic cancer; health implications of premature menopause
Aileen Gariepy, MD: unintended pregnancy, abortion care, miscarriage care, reproductive justice
Jeannine Gerhardt: diminished ovarian reserve, human granulosa cells and oocyte research
Alexander Gleed: fetal ultrasound, placenta, ultrasonic tissue characterization, image analysis
Sharmila Ghosh: early pregnancy loss
Iman Hajirasouliha: AI, in vitro fertilization (IVF), polycystic ovary syndrome (PCOS)
Gunisha Kaur: global health, refugee health, forcibly displaced populations
Alex Kwan: postpartum depression, mental health, antidepressant, drug development
Siu Sylvia Lee: metabolic regulation, gene expression regulation
Marla Lujan: folliculogenesis, menstrual cycle, polycystic ovary syndrome, adolescent reproductive transition
David S. Matteson: AI, data science, statistics
Anna Sophia McKenney: image-guided interventions
Alexander Nikitin: ovarian and endometrial cancers
Nupoor Narula, MD: pregnancy-related aortic complications
Kimberly O’Brien: nutrition, pregnancy, placental nutrient trafficking, bone health, anemia, osteoporosis
Lauren M. Osborne, MD: perinatal mood and anxiety disorders
Sallie Permar: congenital infections, maternal vaccination, maternal-infant immunology
Lisa Placanica: intellectual property, commercial partnerships, new venture creation
Michael Podolsky: cell biology of decidual tissues and parturition; molecular regulation of uterine remodeling
Yi Athena Ren: ovarian biology, reproductive endocrinology, reproductive biotechnology
Laura Sahyoun: inflammatory bowel disease, intestinal ultrasound
Richa Sardana: cancers of the reproductive system, Alzheimer’s disease, protein homeostasis mechanisms
John Schimenti: reproductive genetics; placentation; reproductive aging
Praveen Sethupathy: vulvar squamous cell carcinoma, lupus and microRNAs
Alpana Shukla: gestational diabetes mellitus (GDM), postmenopausal cardiovascular disease risk reduction
Vertika Singh: reproductive biology, primary ovarian insufficiency (POI), endometrial cancer
Heidi Stuhlmann: placental development and disease, fetal programming, transposon dysregulation
Robert Weiss: meiotic mechanisms, genome maintenance pathways in gametogenesis, germ cell tumors
Kayla Wolf: reproductive tissue engineering and mechanobiology
Tamar Zelovich: endometriosis, digital health, symptoms monitoring